These types of medications come in forms that are taken by mouth and forms that are given by injection. eHealthMe is studying from 146,783 Calcium users for its effectiveness, alternative drugs and more. Prolia may cause serious side effects. Let your doctor know if you have questions about which drug is recommended for you. Prolia is injected under the skin. No, weight gain wasnt reported as a side effect of Prolia in clinical trials. If youve been diagnosed with osteoporosis, your doctor may discuss Prolia with you. But if you look at D3 supplements online, youll see that most commercial supplements have higher doses usually either 1,000, 2,000, 5,000 or 10,000 IU. Follow your doctor's instructions. You may wonder how Prolia compares with the alternative drug Reclast. For a basic overview of Prolia, including details about its uses, see this article. You may report side effects to FDA at 1-800-FDA-1088. Serious side effects from Prolia can occur, but they arent common. You should also talk with your doctor if you have nausea during treatment. Take good care of your teeth and gums while you receive Prolia. Some people have developed unusual fractures in their thigh bone. To date, the consensus is that there has been no proven risk of increased cardiovascular risk with intake of calcium supplements. Had parathyroid or thyroid surgery (glands located in your neck), Have been told you have trouble absorbing minerals in your stomach or intestines (malabsorption syndrome), Have kidney problems or are on kidney dialysis, Are taking medicine that can lower your blood calcium levels, Plan to have dental surgery or teeth removed, Are breast-feeding or plan to breast-feed. Prolia contains the same medicine as XGEVA (denosumab). (2022). Some examples are atorvastatin (Lipitor) and rosuvastatin (Crestor). Tell your doctor right away if you become pregnant while taking Prolia. But Prolia is given once every 6 months by a healthcare professional. This drug may not be the right treatment for your condition if you have certain medical conditions or other factors that affect your health. You can discuss the study with your doctor, to ensure that all drug risks and benefits are fully discussed and understood. You might wonder how Prolia and the drug Xgeva compare. Its recommended that calcium and vitamin D supplements be taken They will also explain how much youll be given and how often. Prolia can cause many serious side effects. Tell your doctor if youd like to know more about these drugs. And theyll recommend if its the best option for your condition. Last medically reviewed on November 29, 2022. Rare, long-term side effects of Prolia include fractures of the spine or femur (thighbone). But tingling may be a symptom of side effects such as sciatica and hypocalcemia. Your doctor can help you decide which drug is better for your needs. Whats the Connection Between Estrogen and Osteoporosis? WebAdults ages 19 through 50 should not get more than 2,500 mg calcium total per day (including food and supplements). You may be interested in learning how Prolia compares to the medication Fosamax. Adults over age 50 should not exceed 2,000 mg total per day. And if you have osteoporosis, falling could increase your risk of fractures. It is not safe to receive Prolia during pregnancy. Others may continue for as long as you take the drug, but they can be easily managed. If you have osteoporosis or bone loss, your doctor may discuss Prolia as a treatment option. You may need to have a dental exam before you begin treatment with Prolia. It does the same thing that. Use of the terms female and male in this article refers to sex assigned at birth. These supplements help to prevent a low calcium level while youre taking Prolia. If you develop high cholesterol with Prolia, your doctor can guide you on which treatment options are right for your condition. The fractures may require surgeries, take several months to heal, or both. that's no different than scheduling a visit to the dentist twice a year. They have some similar uses and side effects, but they also have some differences. Its important to tell your doctor if you have serious or ongoing side effects. While youre receiving Prolia treatment, your doctor will monitor your cholesterol levels with regular blood tests. Prolia improves bone mass and increases bone mineral density. If they find any cavities or infection, theyll typically delay having you receive Prolia until your dental problems are treated. If you are pregnant, you should not take Prolia. Talk with your doctor about the risks of using this drug during pregnancy. But this isnt the case with Prolia. Dietary calcium is considered safe, but too much calcium in the form of supplements might have some health risks. Healthline Media does not provide medical advice, diagnosis, or treatment. Low blood calcium level. If youre concerned about hair loss with Prolia, talk with your doctor. The two most common forms of arthritis are osteoarthritis and rheumatoid arthritis (RA). Patients in the study may take other drugs besides Prolia and Calcium. They can also happen if you have certain conditions or if you take certain medications. But unlike generics, which are made for nonbiologic drugs, biosimilars are made for biologic drugs.). After you have taken Prolia out of the refrigerator, you may keep it at room temperature for up to 14 days. Doctors sometimes prescribe Prolia to treat osteoporosis and bone thinning. Certain kidney problems, such as chronic kidney failure, can cause a low calcium level in your blood. Theyll need to confirm that you arent pregnant. Osteopenia They can suggest ways to help relieve these side effects. * Approximation only. Women should inform their doctor if they wish to become pregnant or think they might be pregnant. Your doctor or health care professional may order blood tests and other tests to see how you are doing. Its given to adults who are at high risk for bone fractures. Some items may interact with your medicine. Kidney problems. And some of these side effects are more common with certain uses of Prolia. If your pain is more severe, your doctor may suggest prescription pain medication or physical therapy. Our website services, content, and products are for informational purposes only. Prolia contains the active ingredient denosumab. WebYou should take calcium and vitamin D as your doctor tells you to while you receive Your dentist may have you use a chlorhexidine mouth rinse before and after surgery to reduce your risk for jaw-related side effects. * Sex and gender exist on spectrums. Symptoms may include jaw pain, swelling, numbness, loose teeth, gum infection, or slow healing after injury or surgery involving the gums. You should also take calcium and vitamin D supplements while being You should not breastfeed while using this medicine. low calcium level--muscle spasms or contractions, numbness or tingly feeling (around your mouth, or in your fingers and toes). These side effects include: Your risk for these serious side effects may be higher if youre older and have certain dental procedures. Before your appointment, write down questions, such as: How will Prolia affect my body, mood, or lifestyle? Its recommended that calcium and vitamin D supplements be taken with Prolia. These articles might help: Disclaimer: Medical News Today has made every effort to make certain that all information is factually correct, comprehensive, and up to date. If you miss a dose of Prolia, you should receive your injection as soon as you can. As mentioned above, Prolia contains the active drug denosumab. Prolia is a prescription medicine used to treat bone loss in women who are at high risk for fracture receiving certain treatments What should I know about Prolia vs. Zometa? The conditions and factors to consider include: Upcoming dental procedures. (Vitamin D helps your body absorb calcium.) This makes your bones weak and increases your risk for bone fractures or breaks. WARNING: Please DO NOT STOP MEDICATIONS without first consulting a physician since doing so could be hazardous to your health. Prolia - Patient Information Leaflet (PIL) - (emc) - medicines Phase IV trials are used to detect adverse drug outcomes and monitor drug effectiveness in the real world. If you keep this medicine at home, store it in the original carton in a refrigerator. You are encouraged to report negative side effects of prescription drugs to the FDA. How long will the side effects of Prolia last? If youd like to know more about the differences and similarities of Prolia and Evenity, see this comparison. All rights reserved. Prolia may cause serious side effects. Hair loss with Prolia is rare, and whether Prolia is responsible for this effect isnt known. Your doctor or another healthcare professional will inject Prolia under the skin in one of the following areas: Prolia doses are given as an injection by healthcare professionals once every 6 months. But if your symptoms are serious and you think youre having a medical emergency, immediately call 911 or your local emergency number. Symptoms can be mild or serious and can include: For mild symptoms of an allergic reaction, call your doctor right away. These effects are called interactions. Drug interactions are reported among people who take Prolia and Calcium. Use of the term male in this article refers to sex assigned at birth. But, in some cases, alcohol can affect your balance and increase your risk for falls. Not getting enough calcium in your diet can lead to fragile, brittle bones that are more prone to fractures and disease. Please know that the sponsors of this site are not responsible for content on the site you are about to enter. If you develop a side effect while taking Prolia and want to tell the FDA about it, visit MedWatch. Store in the original container away from heat and light. You Learn more about some of the side effects Prolia may cause. Yoga is an excellent way to manage symptoms of osteoporosis. Dosage of drugs is not considered in the study. This medication guide provides information about the Prolia brand of denosumab. Call your doctor or health care professional for advice if you get a fever, chills or sore throat, or other symptoms of a cold or flu. kidney disease (or if you are on dialysis); a weak immune system (caused by disease or by using certain medicines); hypoparathyroidism (decreased functioning of the parathyroid glands); any condition that makes it hard for your body to absorb nutrients from food (malabsorption); if you are scheduled for a dental procedure; if you cannot take daily calcium and vitamin D; or. What should I know about Prolia vs. Evenity? But if you think youre having a medical emergency, call 911 or your local emergency number. Talk with your doctor about which other treatments are better choices for you. You should take calcium and vitamin D as your doctor tells you to while you receive Prolia. It is created by eHealthMe based on reports of 8,432 people who take Prolia and Calcium from the FDA, and is updated regularly. It is based on denosumab and calcium (the active ingredients of Prolia and Calcium, respectively), and Prolia and Calcium (the brand names). The most common side effects of Prolia in patients with corticosteroid-induced osteoporosis are back pain, high blood pressure, lung infection (bronchitis), and headache. A solid routine can help to strengthen your muscles and bones, which helps to lower your, If you have osteoporosis, diet plays a vital role in managing your condition. In certain cases, Prolia may have contraindications (not be recommended) for you due to a higher risk for side effects. Bring someone with you to your appointment if doing so will help you feel more comfortable. Talk with them about your health and any concerns you have about Prolia and its effects. To prevent osteoporotic fractures, combined calcium and vitamin D supplementation is recommended at the correct dosage (1,0001,200 mg calcium and 800 IU of vitamin D per day). Supplementation should be targeted on vulnerable groups such as elderly and institutionalised people, patients with osteoporosis and individuals on glucocorticoids. Numerous trials have shown that calcium and vitamin D supplementation is effective and safe. In particular, no increased cardiovascular risk was observed. But some females* who received Prolia for osteoporosis after menopause had to stop Prolia treatment due to back pain. Vitamin D The body needs vitamin D to absorb calcium. There is a potential for serious side effects to an unborn child. What are the possible side effects of Prolia? MNT is the registered trade mark of Healthline Media. Prescribing Information and Get the treatment that fits your lifestyle, Stay informed with courtesy reminders, recipes and so much more. Talk with your doctor before starting Prolia treatment. If you develop serious side effects while taking Prolia, call your doctor right away. So treatment with the drug requires you to take daily calcium and vitamin D supplements. They need to know if you have any of these conditions: This medicine is for injection under the skin. Doing so will help to prevent dental problems. If youve already gone through menopause, your risk for bone loss is increased. This medicine may be used for other purposes; ask your health care provider or pharmacist if you have questions. Symptoms of a severe allergic reaction can include swelling under your skin, typically in your eyelids, lips, hands, or feet. For more information, you can refer to the drugs prescribing information. But if the side effects last longer than that, bother you, or become severe, be sure to talk with your doctor or pharmacist. They can treat the infection as needed. Some side effects of Prolia may go away on their own within a few days or weeks after starting treatment. you can take. Prolia and Forteo are both used to treat osteoporosis. To learn more about this side effect, see Side effect specifics below. Tingling or numbness in the hands, feet, and face can develop as a symptom of severe hypocalcemia. Some reports may have incomplete information. Specifically, its used to increase bone mass in: Osteopenia (low bone mass), and low bone mineral density (BMD) can occur with older age. Theyre commonly used to treat osteoporosis. But doing so can cause more bone breakdown and increase your risk for bone fractures. Bone density decreases with time, and some people have a risk of developing weak or brittle bones. have low blood calcium; or are pregnant or plan to become pregnant, as Prolia may harm your unborn baby; or are allergic to denosumab or any ingredients in Prolia. You should make sure you get enough calcium and vitamin D while you are taking this medicine, unless your doctor tells you not to. The use of the eHealthMe site and its content is at your own risk. Place them in a puncture-proof "sharps" container and dispose of it following state or local laws. If you cant properly absorb calcium or other minerals, be sure to talk with your doctor before using Prolia. You may have questions about Prolia and your treatment plan. Like Helpful Hug REPLY 1 reply Mamie | @mamie | Oct Before beginning treatment with Prolia, ask your doctor about the benefits and risks of the drug. Studies have found that Prolia is generally safe and effective to treat osteoporosis and certain types of bone loss. What's the difference between Prolia and Reclast? Osteoporosis How long will I need to keep taking Prolia? Its important to discuss all your concerns with your doctor. And ask your doctor about which drug is right for your condition. * For more information on this side effect, see the Side effect focus section below. All rights reserved. What osteoporosis medications are there, and what side effects do they have? If you have jaw pain or other mouth problems while youre using Prolia, tell your doctor or dentist. Prolia also carries a warning about hypocalcemia, which is a low level of Calcium and Vitamin D: A major role of vitamin D is to help the body absorb calcium and maintain bone density. Its important to practice good oral hygiene during Prolia treatment. If you have bothersome or severe side effects or other problems while taking Prolia and need to stop the medication, your doctor will monitor your bone mineral density. An allergic reaction is possible after using Prolia. If youve had surgery on your thyroid or parathyroid glands, you may have an increased risk of a low level of calcium in your blood. Prolia is used to treat osteoporosis in women after menopause and in men, and in people who are taking corticosteroids for 6 months or more. Prolia is a prescription medicine used to increase bone mass in men with osteoporosis who are at high risk for fracture. Prolia contains the active drug denosumab, and Reclast contains the active drug zoledronic acid. Please see Prolia full Calcium and Vitamin D: Important These treatments may include acetaminophen (Tylenol) or ibuprofen (Advil, Motrin). They can also suggest ways to relieve this side effect. Bisphosphonates, on the other hand, help increase bone thickness and prevent bone breakdown. This was one of the most common side effects in clinical trials of females who received Prolia for osteoporosis after menopause. Prolia is also used to treat glucocorticoid-induced osteoporosis in men and women at high risk of bone fracture. Prolia can also increase this risk. If you notice any tooth or jaw pain, or sensitivity while using Prolia, talk with your doctor or dentist right away. But certain choices and habits accelerate the process. Protect from light and do not freeze. Some examples of these treatments include: Talk with your doctor about other drugs you may need to take with Prolia. Xgeva is another brand of denosumab that treats high calcium levels caused by cancer and prevents bone breaks. Prolia is a prescription medicine used to treat bone loss in men who are at high risk for fracture receiving certain treatments Calcium Supplements Talk to your health care professional or pharmacist for more information. Do not use denosumab if you are pregnant. This is the drugs mechanism of action. Coral calcium is also used in maxillofacial surgery and bone grafting. Patient testimonials represent individual experiences with Prolia. If the side effects seem life threatening or you think youre having a medical emergency, immediately call 911 or your local emergency number. Prolia is also available in a biosimilar form. Prolia may lower the level of calcium in your blood. They do this by slowing the loss of minerals such as calcium from your bones. Be sure to talk with your doctor about which medication is right for you. There are no known interactions with Prolia and other medications, supplements, or other products. Youll likely have questions about your condition and treatment choices. If you have low calcium levels, you should not take Prolia. for breast cancer that has not spread to other parts of the body. For instance: Both Prolia and Forteo are given as injections under your skin. Prolia comes as a solution thats given as an injection under your skin. Lifestyle changes that can help improve cholesterol levels include exercising regularly and eating a healthy diet. Osteoporosis Medications (Bisphosphonates) - Johns Hopkins Nausea can sometimes be a symptom of severe constipation. The most common side effects of Prolia in patients receiving certain treatments for prostate or breast cancer are joint pain, back pain, pain in your arms and legs, and muscle pain. Prolia and Xgeva both contain the active drug denosumab, but they are not approved to treat all of the same conditions. Instead, your doctor may recommend that you make certain changes to your diet, such as increasing your calcium and vitamin D intake. Based on your dental history, your doctor can discuss with you the risks of using Prolia. (A low blood calcium level is a possible side effect of Prolia.). Youll receive Prolia doses from a healthcare professional. Learn how to slow it down and fortify your body against it. The absence of warnings or other information for a given drug does not indicate that the drug or drug combination is safe, effective, or appropriate for all patients or all specific uses. You can use the study as a second opinion to make health care decisions. Follow your doctor's instructions about any restrictions on food, beverages, or activity. Its a, Forteos active ingredient is teriparatide. The list below may not include all possible serious side effects of the drug. Medically reviewed by Sanjai Sinha, MD. Drug class: Miscellaneous bone resorption inhibitors. To learn more about these two drugs, check out this drug article. This is because the drug may be harmful to a growing fetus. We link primary sources including studies, scientific references, and statistics within each article and also list them in the resources section at the bottom of our articles. (To learn more, see the Precautions for Prolia section below.). Keep in mind that side effects of a drug can depend on: Additionally, you may experience different side effects from those listed below based on the condition youre treating with Prolia. supplements Youll receive Prolia doses from a healthcare professional. See additional information. They may give you tips on managing a body weight thats healthy for you. Prolia is sometimes used in people whose bone fracture is caused by certain medicines or cancer treatments. Data sources include IBM Watson Micromedex (updated 2 Apr 2023), Cerner Multum (updated 17 Apr 2023), ASHP (updated 10 Apr 2023) and others. If youd like a detailed comparison of Prolia versus Boniva, view this article. WebDrug interactions are reported among people who take Prolia and Calcium. Your doctor will recommend the dosage of Prolia thats right for you. Different individuals may respond to medication in different ways. However, this article should not be used as a substitute for the knowledge and expertise of a licensed healthcare professional. Your doctor can provide more information to you about the benefits and risks of using Prolia for your condition. Peripheral edema is a less common side effect that was reported in clinical studies of females* who received Prolia for osteoporosis after menopause. Continue reading, Prolia (denosumab) has not been associated with weight gain in clinical studies. Keep in mind that Prolia is used to help strengthen your bones and prevent fractures, which may happen with falls. Your doctor will order blood tests to check your level before you start using Prolia and regularly during your treatment. Boniva contains the active drug ibandronate, but Prolia contains the active drug denosumab. You should always consult your doctor or another healthcare professional before taking any medication. To learn how Prolia and Tymlos are alike and different, see this comparison. Your doctor can discuss with you how to manage side effects and whether youll need to stop taking Prolia due to side effects. Every 6 months youll get another dose of Prolia. Common interactions include nausea among females and fatigue among males. Xgeva is another brand of denosumab used to prevent bone fractures and other skeletal conditions in people with tumors that have spread to the bone. Continue reading, Prolia is a prescription medicine injected under the skin (called a subcutaneous injection) and is given once every 6 months. for prostate cancer that has not spread to other parts of the body.

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